The ubiquitin-specific protease 8 antagonizes melatonin-induced endocytic degradation of MT1 receptor to promote lung adenocarcinoma growth

Introduction: The human genome encodes two melatonin receptors (MT1 and MT2) that relay melatonin signals to cellular interior.Accumulating evidence has linked melatonin to multiple health benefits, among which its anticancer effects have become well-established.However, the implications Breadboards of its receptors in lung adenocarcinoma have so f

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Effects of Biochar and Compost Application on Soil Properties and on the Growth and Yield of Hot Pepper (Capsicum annuum L.)

Improper depositions of organic waste threaten the environment.On the other hand, intensive soil cultivation, inappropriate utilization of inorganic fertilizers, and inadequate soil management practices in the study area resulted in soil fertility reduction and poor crop growth.The addition of organic fertilizers from organic waste (biochar and com

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A Flexible Strain Sensor Based on a Conductive Polymer Composite for in situ Measurement of Parachute Canopy Deformation

A Childs Table sensor based on a Conductive Polymer Composite (CPC), fully compatible with a textile substrate and its general properties, has been developed in our laboratory, and its electromechanical characterization is presented herein.In particular the effects of strain rate (from 10 to 1,000 mm/min) and of repeated elongation cycles on the se

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